Title : LINCS Dataset-Based Repositioning of Dutasteride as an Anti-Neuroinflammation Agent.

Pub. Date : 2021 Oct 26

PMID : 34827410






2 Functional Relationships(s)
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1 The results showed that dutasteride significantly reduced the levels of IL-6 and TNF-alpha in the supernatants of LPS-stimulated BV2 cells, and decreased the levels of IL-6 in the hippocampus and plasma, and the number of activated microglia in the brain of LPS administration mice. Dutasteride interleukin 6 Mus musculus
2 The results showed that dutasteride significantly reduced the levels of IL-6 and TNF-alpha in the supernatants of LPS-stimulated BV2 cells, and decreased the levels of IL-6 in the hippocampus and plasma, and the number of activated microglia in the brain of LPS administration mice. Dutasteride interleukin 6 Mus musculus