Title : Metabolic Imbalance Effect on Retinal Müller Glial Cells Reprogramming Capacity: Involvement of Histone Deacetylase SIRT6.

Pub. Date : 2021

PMID : 34804128






1 Functional Relationships(s)
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1 We found that the combination of high glucose and oxidative stress induced a decrease in the levels of the marker glutamine synthetase, and an increase in the migration capacity of the cells suggesting that these experimental conditions could induce some degree of dedifferentiation and favor the migration ability. Glucose glutamate-ammonia ligase (glutamine synthetase) Mus musculus