Pub. Date : 2021
PMID : 34760922
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | STAT3 and IL-6 Contribute to Corticosteroid Resistance in an OVA and Ozone-induced Asthma Model with Neutrophil Infiltration. | Ozone | interleukin 6 | Homo sapiens |
| 2 | A positive correlation between IL-6 or IL-17A and STAT3 and negative correlation between SOCS3 and STAT3 were shown, suggesting that the IL-6/STAT3 pathway may be involved in OVA + ozone-induced corticosteroid-resistant airway inflammation. | Ozone | interleukin 6 | Homo sapiens |
| 3 | A positive correlation between IL-6 or IL-17A and STAT3 and negative correlation between SOCS3 and STAT3 were shown, suggesting that the IL-6/STAT3 pathway may be involved in OVA + ozone-induced corticosteroid-resistant airway inflammation. | Ozone | interleukin 6 | Homo sapiens |
| 4 | The IL-6/STAT3 pathway may contribute to corticosteroid insensitivity in OVA + ozone-induced neutrophilic airway inflammation through regulation of Th17 cells and could provide new targets for individual treatment of corticosteroid resistance in asthma. | Ozone | interleukin 6 | Homo sapiens |