Title : The effect of fatty diacid acylation of human PYY3-36 on Y2 receptor potency and half-life in minipigs.

Pub. Date : 2021 Oct 27

PMID : 34707178






1 Functional Relationships(s)
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1 To obtain long half-lives allowing for up to once-weekly dosing regimen, fatty acid acylation (lipidation) have been used to non-covalently associate the peptide to serum albumin thus serving as a circulating depot. Fatty Acids albumin Homo sapiens