Title : Inhibition of ABCC1 Decreases cAMP Egress and Promotes Human Airway Smooth Muscle Cell Relaxation.

Pub. Date : 2022 Jan

PMID : 34648729






1 Functional Relationships(s)
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1 Using human airway smooth muscle (HASM) cells in culture as a model, here we report that activation of the cell surface beta2-adrenoceptor (beta2AR), a Gs-coupled G protein-coupled receptor (GPCR), evokes cAMP egress to the extracellular space. Cyclic AMP adrenoceptor beta 2 Homo sapiens