Pub. Date : 2021 Nov
PMID : 34533218
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 2-Arachidonoyl glycerol potently induces cholecystokinin secretion in murine enteroendocrine STC-1 cells via cannabinoid receptor CB1. | glyceryl 2-arachidonate | cholecystokinin | Mus musculus |
| 2 | Among four 2-MAG (2-palmitoyl, 2-oleoyl, 2-linoleoyl, and 2-arachidonoyl monoacylglycerols) examined, 2-arachidonoyl glycerol (2-AG) potently stimulated CCK secretion in a dose-dependent manner. | glyceryl 2-arachidonate | cholecystokinin | Mus musculus |
| 3 | Among four 2-MAG (2-palmitoyl, 2-oleoyl, 2-linoleoyl, and 2-arachidonoyl monoacylglycerols) examined, 2-arachidonoyl glycerol (2-AG) potently stimulated CCK secretion in a dose-dependent manner. | glyceryl 2-arachidonate | cholecystokinin | Mus musculus |
| 4 | Both arachidonic acid and 2-AG stimulated CCK secretion at 100 muM, but only 2-AG did at 50 muM. | glyceryl 2-arachidonate | cholecystokinin | Mus musculus |
| 5 | 2-AG-induced CCK secretion but not arachidonic acid-induced CCK secretion was attenuated by treatment with a cannabinoid receptor 1 (CB1) antagonist. | glyceryl 2-arachidonate | cholecystokinin | Mus musculus |
| 6 | These results indicate that a specific 2-MAG, 2-AG, directly stimulates CCK secretion via CB1. | glyceryl 2-arachidonate | cholecystokinin | Mus musculus |