Title : Beneficial Effects of Dietary Polyphenols in the Prevention and Treatment of NAFLD: Cell-Signaling Pathways Underlying Health Effects.

Pub. Date : 2022

PMID : 34525916






1 Functional Relationships(s)
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1 Data reported for hydroxytyrosol suggest that the activation of the hepatic PPAR-alpha-FGF21-AMPK-PGC-1alpha signaling cascade is associated with fatty acid oxidation enhancement, de novo lipogenesis diminution and recovery of mitochondrial function, a contention that is supported by the actions of several polyphenols on specific components of this signaling pathway. Fatty Acids protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens