Title : Nanocurcumin alleviates inflammation and oxidative stress in LPS-induced mastitis via activation of Nrf2 and suppressing TLR4-mediated NF-κB and HMGB1 signaling pathways in rats.

Pub. Date : 2022 Feb

PMID : 34482462






2 Functional Relationships(s)
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1 Nanocurcumin alleviates inflammation and oxidative stress in LPS-induced mastitis via activation of Nrf2 and suppressing TLR4-mediated NF-kappaB and HMGB1 signaling pathways in rats. nanocurcumin toll-like receptor 4 Rattus norvegicus
2 The results showed that nanocurcumin significantly attenuated the lipid peroxidation (MDA), oxidized glutathione, the release of pro-inflammatory cytokines (TNF-alpha and IL-1beta), and the gene expression of TLR4, NF-kappaB p65, and HMGB1. nanocurcumin toll-like receptor 4 Rattus norvegicus