Title : Single-molecule measurements reveal that PARP1 condenses DNA by loop stabilization.

Pub. Date : 2021 Aug

PMID : 34380612






2 Functional Relationships(s)
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1 PARP inhibitors do not affect the level of condensation of undamaged DNA but act to block condensation reversal for damaged DNA in the presence of NAD+ Our findings suggest a mechanism for PARP1 in the organization of chromatin structure. NAD poly(ADP-ribose) polymerase 1 Homo sapiens
2 PARP inhibitors do not affect the level of condensation of undamaged DNA but act to block condensation reversal for damaged DNA in the presence of NAD+ Our findings suggest a mechanism for PARP1 in the organization of chromatin structure. NAD poly(ADP-ribose) polymerase 1 Homo sapiens