Title : DNMT1-mediated PPARĪ± methylation aggravates damage of retinal tissues in diabetic retinopathy mice.

Pub. Date : 2021 Aug 6

PMID : 34362460






2 Functional Relationships(s)
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1 PPARalpha overexpression suppressed apoptosis and ROS levels of HRCPs, which was rescued by DNMT1 up-regulation. Reactive Oxygen Species peroxisome proliferator activated receptor alpha Mus musculus
2 CONCLUSION: DNMT1-mediated PPARalpha methylation promotes apoptosis and ROS levels of HRCPs and aggravates damage of retinal tissues in DR mice. Reactive Oxygen Species peroxisome proliferator activated receptor alpha Mus musculus