Title : Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1.

Pub. Date : 2021 Sep 8

PMID : 34314389

1 Functional Relationships(s)
Compound Name
Protein Name
1 Lsd1 knockout reduces NAD+-dependent SIRT1 and SIRT7 deacetylase activity, leading to hyperacetylation and hypofunctioning of GABPbeta and PGC-1alpha, the major transcriptional factor/cofactor for nuclear-encoded mitochondrial genes. NAD sirtuin 1 Mus musculus