Title : NOX2 Activation in COVID-19: Possible Implications for Neurodegenerative Diseases.

Pub. Date : 2021 Jun 11

PMID : 34208136






1 Functional Relationships(s)
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1 SARS-CoV-2 infection occurs through the interaction of the viral protein Spike with the angiotensin II receptor (ACE 2), leading to an increase of angiotensin II and activation of nicotinamide adenine dinucleotide phosphate oxidase2 (NOX2), resulting in the release of both reactive oxygen species (ROS) and inflammatory molecules. NAD surface glycoprotein Severe acute respiratory syndrome coronavirus 2