Title : MiR-100-5p regulates cardiac hypertrophy through activation of autophagy by targeting mTOR.

Pub. Date : 2021 Sep

PMID : 34138410






4 Functional Relationships(s)
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1 MiR-100-5p regulates cardiac hypertrophy through activation of autophagy by targeting mTOR. mir-100-5p mechanistic target of rapamycin kinase Rattus norvegicus
2 Mechanistic investigation has found that miR-100-5p promote autophagy by targeting mTOR. mir-100-5p mechanistic target of rapamycin kinase Rattus norvegicus
3 Inhibition of autophagy by 3-methyladenine (3-MA) or mTOR overexpression could reverse the function of miR-100-5p in cardiac hypertrophy. mir-100-5p mechanistic target of rapamycin kinase Rattus norvegicus
4 These results elucidate that miR-100-5p promoted the pathogenesis of cardiac hypertrophy through autophagy activation by targeting mTOR. mir-100-5p mechanistic target of rapamycin kinase Rattus norvegicus