Title : Cardamonin Attenuates Inflammation and Oxidative Stress in Interleukin-1β-Stimulated Osteoarthritis Chondrocyte through the Nrf2 Pathway.

Pub. Date : 2021 May 27

PMID : 34072123






2 Functional Relationships(s)
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1 In the current study, we determined that treating interleukin-1 beta (IL-1beta-stimulated chondrocyte cells) with cardamonin significantly reduced the release of nitric oxide (NO) and prostaglandin E2 (PGE2) and significantly inhibited the expression of pro-inflammatory proteins, including inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX2). Dinoprostone interleukin 1 beta Homo sapiens
2 In the current study, we determined that treating interleukin-1 beta (IL-1beta-stimulated chondrocyte cells) with cardamonin significantly reduced the release of nitric oxide (NO) and prostaglandin E2 (PGE2) and significantly inhibited the expression of pro-inflammatory proteins, including inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX2). Dinoprostone interleukin 1 beta Homo sapiens