Title : DNMT3A Mutation-Induced CDK1 Overexpression Promotes Leukemogenesis by Modulating the Interaction between EZH2 and DNMT3A.

Pub. Date : 2021 May 22

PMID : 34067359






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CDK1 selective inhibitor CGP74514A (CGP) and the pan-CDK inhibitor flavopiridol (FLA) arrested OCI-AML3 cells in the G2/M phase, and induced cell apoptosis. alvocidib cyclin dependent kinase 1 Homo sapiens
2 CDK1 selective inhibitor CGP74514A (CGP) and the pan-CDK inhibitor flavopiridol (FLA) arrested OCI-AML3 cells in the G2/M phase, and induced cell apoptosis. alvocidib cyclin dependent kinase 1 Homo sapiens