Title : Differences in PARP Inhibitors for the Treatment of Ovarian Cancer: Mechanisms of Action, Pharmacology, Safety, and Efficacy.

Pub. Date : 2021 Apr 19

PMID : 33921561






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 PARP inhibitors (PARPi) are able to interact with the binding site for PARP cofactor (NAD+) and trapping PARP on the DNA. NAD poly(ADP-ribose) polymerase 1 Homo sapiens
2 PARP inhibitors (PARPi) are able to interact with the binding site for PARP cofactor (NAD+) and trapping PARP on the DNA. NAD poly(ADP-ribose) polymerase 1 Homo sapiens
3 PARP inhibitors (PARPi) are able to interact with the binding site for PARP cofactor (NAD+) and trapping PARP on the DNA. NAD poly(ADP-ribose) polymerase 1 Homo sapiens