Title : A pain killer without analgesic tolerance designed by co-targeting PSD-95-nNOS interaction and α2-containning GABAARs.

Pub. Date : 2021

PMID : 33897893






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A dual-target compound ZL006-05 produced by linking ZL006 and (+)-borneol through an ester bond blocked nNOS-PSD-95 interaction and potentiated alpha2-containing GABAAR selectively. Esters discs large MAGUK scaffold protein 4 Homo sapiens