Title : Characterization of the Signaling Modalities of Prostaglandin E2 Receptors EP2 and EP4 Reveals Crosstalk and a Role for Microtubules.

Pub. Date : 2020

PMID : 33643295






2 Functional Relationships(s)
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1 While both EP2 and EP4 signaling leads to an elevation of intracellular cyclic adenosine monophosphate (cAMP) levels through the stimulating Galphas protein, EP4 also couples to the inhibitory Galphai protein to decrease the production of cAMP. Cyclic AMP gastrin Homo sapiens
2 While both EP2 and EP4 signaling leads to an elevation of intracellular cyclic adenosine monophosphate (cAMP) levels through the stimulating Galphas protein, EP4 also couples to the inhibitory Galphai protein to decrease the production of cAMP. Cyclic AMP gastrin Homo sapiens