Title : Curcumin Nanoparticle Enhances the Anticancer Effect of Cisplatin by Inhibiting PI3K/AKT and JAK/STAT3 Pathway in Rat Ovarian Carcinoma Induced by DMBA.

Pub. Date : 2020

PMID : 33536913






2 Functional Relationships(s)
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1 Co-treatment of cisplatin and nanocurcumin also reduced JAK expression, STAT3 phosphorylation, and reduced IL-6 concentrations. nanocurcumin signal transducer and activator of transcription 3 Rattus norvegicus
2 Altogether, nanocurcumin, given as a co-treatment with cisplatin has therapeutic potential in ovarian cancer models by inhibiting proliferation through downregulation of PI3K/Akt and JAK/STAT3 signaling pathways. nanocurcumin signal transducer and activator of transcription 3 Rattus norvegicus