Title : Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2.

Pub. Date : 2021 Feb

PMID : 33360775






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A significant reduction of postsynaptic density protein 95 (PSD95) and a concurrent increase in cleaved caspase-3 protein levels have been demonstrated in neurons co-cultured with oxysterol-treated astrocytes, pointing out that mediators released by astrocytes have an impact on neurons. Oxysterols caspase 3 Mus musculus