Title : Effects of CYP46A1 Inhibition on Long-Term-Depression in Hippocampal Slices ex vivo and 24S-Hydroxycholesterol Levels in Mice in vivo.

Pub. Date : 2020

PMID : 33192294






1 Functional Relationships(s)
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1 Our results suggest that rodents show similarity to humans for studying the impact of CYP46A1 inhibitors and that rapid, local modulation of oxysterols can be achieved through CYP46A1 inhibition. Oxysterols cytochrome P450 family 46 subfamily A member 1 Homo sapiens