Title : Human mass balance, metabolism, and cytochrome P450 phenotyping of lusutrombopag.

Pub. Date : 2021 Mar

PMID : 33125290






1 Functional Relationships(s)
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1 Our in vitro metabolism study of lusutrombopag indicated that beta-oxidation was a subsequent metabolism of omega-oxidation and CYP4 enzymes, including CYP4A11, were the major isozymes contributing to omega-oxidation. lusutrombopag cytochrome P450 family 4 subfamily A member 11 Homo sapiens