Title : Non-Transcriptional and Translational Function of Canonical NF-κB Signaling in Activating ERK1/2 in IL-1β-Induced COX-2 Expression in Synovial Fibroblasts.

Pub. Date : 2020

PMID : 33117381

1 Functional Relationships(s)
Compound Name
Protein Name
1 The pro-inflammatory cytokine interleukin 1beta (IL-1beta) induces the synthesis of prostaglandin E2 by upregulating cyclooxygenase-2 (COX-2) in the synovial tissue of individuals with autoimmune diseases, such as rheumatoid arthritis (RA). Dinoprostone interleukin 1 beta Homo sapiens