Title : Toll-like receptor 5 deficiency diminishes doxorubicin-induced acute cardiotoxicity in mice.

Pub. Date : 2020

PMID : 33042267






1 Functional Relationships(s)
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1 Mechanistically, the effects of TLR5 were largely attributed to direct interaction with spleen tyrosine kinase to activate NADPH oxidase (NOX) 2, increasing the production of superoxide and subsequent activation of p38. Superoxides cytochrome b-245, beta polypeptide Mus musculus