Title : 2,5-dimethylcelecoxib improves immune microenvironment of hepatocellular carcinoma by promoting ubiquitination of HBx-induced PD-L1.

Pub. Date : 2020 Oct

PMID : 33028694






1 Functional Relationships(s)
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1 BACKGROUND: 2,5-dimethylcelecoxib (DMC) is a targeted inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), a key enzyme in the PGE2 synthesis pathway of inflammatory mediators. Dinoprostone prostaglandin E synthase Homo sapiens