Title : PARP inhibition as frontline therapy in ovarian cancer.

Pub. Date : 2020 Sep

PMID : 33006584






2 Functional Relationships(s)
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1 PARP inhibitors are also approved as maintenance treatment following a response to platinum-based therapy in the recurrent setting, irrespective of biomarker status. Platinum poly(ADP-ribose) polymerase 1 Homo sapiens
2 Additionally, PARP inhibitors are approved as third-line treatment and beyond in lieu of chemotherapy for patients with BRCA-associated cancers, and as fourth-line treatment and beyond for patients with platinum-sensitive homologous recombination-deficient tumors. Platinum poly(ADP-ribose) polymerase 1 Homo sapiens