Title : Inhibiting the PGE2 Receptor EP2 Mitigates Excitotoxicity and Ischemic Injury.

Pub. Date : 2020 Aug 14

PMID : 32832866






2 Functional Relationships(s)
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1 Prostaglandin E2 (PGE2) is elevated in the brain by excitotoxic insults and, in turn, aggravates the neurotoxicity mainly through acting on its Galphas-coupled receptor EP2, inspiring a therapeutic strategy of targeting this key proinflammatory pathway. Dinoprostone prostaglandin E receptor 2 Rattus norvegicus
2 Prostaglandin E2 (PGE2) is elevated in the brain by excitotoxic insults and, in turn, aggravates the neurotoxicity mainly through acting on its Galphas-coupled receptor EP2, inspiring a therapeutic strategy of targeting this key proinflammatory pathway. Dinoprostone prostaglandin E receptor 2 Rattus norvegicus