Title : Debio 1143 and high-dose cisplatin chemoradiotherapy in high-risk locoregionally advanced squamous cell carcinoma of the head and neck: a double-blind, multicentre, randomised, phase 2 study.

Pub. Date : 2020 Sep

PMID : 32758455






1 Functional Relationships(s)
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1 The radiosensitising effect of Debio 1143 is mediated through caspase activation and TNF, IFNgamma, CD8 T cell-dependent pathways. N-benzhydryl-5-(2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo(1,2-a)(1,5)diazocine-8-carboxamide CD8a molecule Homo sapiens