Title : A Rare Mutation in an Infant-Derived HIV-1 Envelope Glycoprotein Alters Interprotomer Stability and Susceptibility to Broadly Neutralizing Antibodies Targeting the Trimer Apex.

Pub. Date : 2020 Sep 15

PMID : 32669335






1 Functional Relationships(s)
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1 In conclusion, we report a naturally selected viral mutation, L184F, that influenced a change in the conformation of the Env trimer apex as a mechanism of escape from contemporaneous plasma V2 apex-targeted nAbs. nabs endogenous retrovirus group K member 20 Homo sapiens