Title : Oxymatrine Attenuates Dopaminergic Neuronal Damage and Microglia-Mediated Neuroinflammation Through Cathepsin D-Dependent HMGB1/TLR4/NF-κB Pathway in Parkinson's Disease.

Pub. Date : 2020

PMID : 32528295






2 Functional Relationships(s)
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1 Oxymatrine Attenuates Dopaminergic Neuronal Damage and Microglia-Mediated Neuroinflammation Through Cathepsin D-Dependent HMGB1/TLR4/NF-kappaB Pathway in Parkinson"s Disease. oxymatrine nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 It is worth noting that overexpression of CathD reversed OMT-targeted inhibition of HMGB1/TLR4/NF-kappaB signaling and OMT-produced neuroprotection in reconstituted neuron-microglia co-cultures. oxymatrine nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus