Pub. Date : 2020 Jul
PMID : 32504419
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | By using a previously established mouse model of depression induced by combined delivery of IFN-alpha and polyinosinic:polycytidylic acid (poly(I:C)), a TLR3 agonist, we provide evidence that IFN-alpha and poly(I:C) reduce apical dendritic spine density in the hippocampal CA1 area ex vivo via mechanisms involving decreased TrkB signaling. | Poly C | neurotrophic tyrosine kinase, receptor, type 2 | Mus musculus |