Title : Sangguayin preparation prevents palmitate-induced apoptosis by suppressing endoplasmic reticulum stress and autophagy in db/db mice and MIN6 pancreatic β-cells.

Pub. Date : 2020 Jun

PMID : 32503738






1 Functional Relationships(s)
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1 Hence, SGY-P therapy exhibited a protective effect on pancreatic beta-cells by decreasing the expression of cleaved caspase-3, cleaved PARP and Bax, and increasing Bcl-2 by suppressing ER stress (Bip/XBP1/IRE1alpha/CHOP/Caspase-12) and autophagy (LC3/p62/Atg5) pathways.2/Atg5) pathways. sgy-p caspase 12 Mus musculus