Title : Combination of sirtuin 3 and hyperoxia diminishes tumorigenic properties of MDA-MB-231 cells.

Pub. Date : 2020 Aug 1

PMID : 32428596






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 AIMS: Since the role of the major mitochondrial NAD+-dependent deacetylase, sirtuin 3 (Sirt3), is differential in cancer, opposite to the well-known tumor-suppressing effect of hyperoxia, this study aimed to investigate the role of Sirt3 in triple-negative breast cancer (TNBC) cell line MDA-MB-231 upon hyperoxic (95% O2) conditions. NAD sirtuin 3 Homo sapiens