Title : Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma.

Pub. Date : 2020 Apr 25

PMID : 32344880






1 Functional Relationships(s)
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1 Nelfinavir decreases the total protein level of TCF11/Nrf1 and inhibits TCF11/Nrf1 proteolytic processing, likely by interfering with the DDI2 protease, and therefore reduces the TCF11/Nrf1 protein level in the nucleus. Nelfinavir DNA damage inducible 1 homolog 2 Homo sapiens