Title : Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions.

Pub. Date : 2020 Jul 1

PMID : 32294204






1 Functional Relationships(s)
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1 The apparent half-maximal inhibitory concentrations for OSTalpha/beta-mediated bile acid (5microM) transport inhibition by fidaxomicin, troglitazone sulfate and ethinyl estradiol were: 210, 334 and 1050microM, respectively, for taurochenodeoxycholate; 97.6, 333 and 337microM, respectively, for glycochenodeoxycholate; 140, 265 and 527microM, respectively, for taurocholate; 59.8, 102 and 117microM, respectively, for glycocholate. troglitazone sulfate solute carrier family 51 subunit alpha Homo sapiens