Title : One-pot synthesis of glutathione-responsive amphiphilic drug self-delivery micelles of doxorubicin-disulfide-methoxy polyethylene glycol for tumor therapy.

Pub. Date : 2018 Jan 7

PMID : 32254191






2 Functional Relationships(s)
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1 The accumulative release rate of DOX analogues with drug activity from the micelles was 67.9% under pH 7.4 and GSH = 1 mg mL-1 conditions after 72 h. The cell uptake experiment showed that the micelles of DOX-DSDA-PEG were indeed taken up by A549 cells and distributed to cell nuclei. Doxorubicin L1 cell adhesion molecule Mus musculus
2 The accumulative release rate of DOX analogues with drug activity from the micelles was 67.9% under pH 7.4 and GSH = 1 mg mL-1 conditions after 72 h. The cell uptake experiment showed that the micelles of DOX-DSDA-PEG were indeed taken up by A549 cells and distributed to cell nuclei. Doxorubicin L1 cell adhesion molecule Mus musculus