Title : Mitochondrial superoxide mediates PM2.5-induced cytotoxicity in human pulmonary lymphatic endothelial cells.

Pub. Date : 2020 Aug

PMID : 32222623

1 Functional Relationships(s)
Compound Name
Protein Name
1 Mechanistically, we provide compelling evidence that PM2.5 reduces SOD2 expression through activation of Akt pathway, which leads to a disruption of mitochondrial redox homeostasis characterized by increased accumulation of mitochondrial superoxide. Superoxides superoxide dismutase 2 Homo sapiens