Title : Helicobacter pylori CagA oncoprotein interacts with SHIP2 to increase its delivery into gastric epithelial cells.

Pub. Date : 2020 May

PMID : 32198795






1 Functional Relationships(s)
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1 In contrast to the case of SHP2, however, SHIP2 binds more strongly to EPIYA-C than to EPIYA-D. Interaction with CagA tethers SHIP2 to the plasma membrane, where it mediates production of phosphatidylinositol 3,4-diphosphate [PI(3,4)P2 ]. phosphatidylinositol 3,4-diphosphate S100 calcium binding protein A8 (calgranulin A) Mus musculus