Title : Measurement of the affinities of heparins, naturally occurring glycosaminoglycans, and other sulfated polymers for antithrombin III and thrombin.

Pub. Date : 1988 Oct

PMID : 3218731






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Measurement of the affinities of heparins, naturally occurring glycosaminoglycans, and other sulfated polymers for antithrombin III and thrombin. Glycosaminoglycans serpin family C member 1 Homo sapiens
2 This has been used to compare the binding of a range of glycosaminoglycans and other sulfated polymers to antithrombin III and thrombin, a major inhibitor of and a central protease in the coagulation system, respectively. Glycosaminoglycans serpin family C member 1 Homo sapiens
3 The results are consistent with the binding of naturally occurring glycosaminoglycans to antithrombin III solely through the well-defined antithrombin III-binding pentasaccharide found in heparin, the apparent affinity of a preparation depending upon its content of this pentasaccharide. Glycosaminoglycans serpin family C member 1 Homo sapiens
4 The results are consistent with the binding of naturally occurring glycosaminoglycans to antithrombin III solely through the well-defined antithrombin III-binding pentasaccharide found in heparin, the apparent affinity of a preparation depending upon its content of this pentasaccharide. Glycosaminoglycans serpin family C member 1 Homo sapiens