Title : Synthetic analogues of 2-oxo acids discriminate metabolic contribution of the 2-oxoglutarate and 2-oxoadipate dehydrogenases in mammalian cells and tissues.

Pub. Date : 2020 Feb 5

PMID : 32024885






1 Functional Relationships(s)
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1 Using succinyl, glutaryl and adipoyl phosphonates on the enzyme preparations from tissues with varied DHTKD1 expression reveals the contributions of OADH and OGDH to oxidation of 2-oxoadipate and 2-oxoglutarate in vitro. glutaryl-coenzyme A dehydrogenase E1 and transketolase domain containing 1 Homo sapiens