Title : Taurine protects against cardiac dysfunction induced by pressure overload through SIRT1-p53 activation.

Pub. Date : 2020 Feb 1

PMID : 32017914






2 Functional Relationships(s)
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1 However, EX-527(inhibitor of SIRT1) decreased NAD+/NADH ratio and increased acetyl-p53 levels, and abolished the cardioprotective effects of taurine on mice subjected to TAC and increased apoptosis and oxidative stress. NAD sirtuin 1 Mus musculus
2 However, EX-527(inhibitor of SIRT1) decreased NAD+/NADH ratio and increased acetyl-p53 levels, and abolished the cardioprotective effects of taurine on mice subjected to TAC and increased apoptosis and oxidative stress. NAD sirtuin 1 Mus musculus