Title : mRNA as a Novel Treatment Strategy for Hereditary Spastic Paraplegia Type 5.

Pub. Date : 2019 Dec 13

PMID : 31828178






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Lack of CYP7B1 leads to an accumulation of its oxysterol substrates, in particular 25-hydroxycholesterol and 27-hydroxycholesterol that are able to cross the blood-brain barrier and have neurotoxic properties. 27-hydroxycholesterol cytochrome P450 family 7 subfamily B member 1 Homo sapiens