Title : Mutant p53 induces SIRT3/MnSOD axis to moderate ROS production in melanoma cells.

Pub. Date : 2020 Jan 15

PMID : 31812668






2 Functional Relationships(s)
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1 We also demonstrate that mutant p53 induces the expression of Sirtuin3 (SIRT3), a major mitochondrial NAD+-dependent deacetylase, stimulating MnSOD deacetylation and enzymatic activity. NAD sirtuin 3 Homo sapiens
2 We also demonstrate that mutant p53 induces the expression of Sirtuin3 (SIRT3), a major mitochondrial NAD+-dependent deacetylase, stimulating MnSOD deacetylation and enzymatic activity. NAD sirtuin 3 Homo sapiens