Title : Interleukin 1β and Prostaglandin E2 affect expression of DNA methylating and demethylating enzymes in human gingival fibroblasts.

Pub. Date : 2020 Jan

PMID : 31810887

1 Functional Relationships(s)
Compound Name
Protein Name
1 Here we show that exposure of human gingival fibroblasts to IL-1beta increases expression of maintenance methyltransferase DNMT1 but decreases expression of de novo methyltransferase DNMT3a and the demethylating enzyme TET1, while exposure to PGE2 decreases expression of all three enzymes. Dinoprostone interleukin 1 beta Homo sapiens