Title : Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms.

Pub. Date : 2019 Dec

PMID : 31768065






1 Functional Relationships(s)
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1 In this study, we uncovered activating mutations in CSF1R and rearrangements in RET and ALK that conferred dramatic responses to selective inhibition of RET (selpercatinib) and crizotinib, respectively, in patients with histiocytosis. Crizotinib ret proto-oncogene Homo sapiens