Title : FTY720-Mitoxy reduces synucleinopathy and neuroinflammation, restores behavior and mitochondria function, and increases GDNF expression in Multiple System Atrophy mouse models.

Pub. Date : 2020 Mar

PMID : 31751571






1 Functional Relationships(s)
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1 Our prior studies using the parent compound FTY720, a food and drug administration (FDA) approved immunosuppressive for multiple sclerosis, reveal that FTY720 protects parkinsonian mice by increasing BDNF. Fingolimod Hydrochloride brain derived neurotrophic factor Mus musculus