Title : The anticoagulant effect of Apis mellifera phospholipase A2 is inhibited by CORM-2 via a carbon monoxide-independent mechanism.

Pub. Date : 2020 Jan

PMID : 31679116






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Exposure of PLA2 to a Ru-based CORM in the presence of histidine-rich human albumin resulted in loss of inhibition of PLA2. Histidine phospholipase A2 group IB Homo sapiens
2 Exposure of PLA2 to a Ru-based CORM in the presence of histidine-rich human albumin resulted in loss of inhibition of PLA2. Histidine phospholipase A2 group IB Homo sapiens
3 Ru-based CORM likely inhibit bee venom PLA2 anticoagulant activity via formation of reactive Ru species that bind to histidine residues of the enzyme. Histidine phospholipase A2 group IB Homo sapiens