Title : Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism.

Pub. Date : 2019 Oct 29

PMID : 31665640






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 GLUL-deficient PDAC cells are capable of the TCA cycle but defective in aKG-coupled glutamine biosynthesis and subsequent nitrogen anabolic processes. Nitrogen glutamate-ammonia ligase (glutamine synthetase) Mus musculus
2 Therefore, GLUL-mediated glutamine biosynthesis couples the TCA cycle with nitrogen anabolism and plays a critical role in PDAC. Nitrogen glutamate-ammonia ligase (glutamine synthetase) Mus musculus