Title : ROS-dependent DNA damage contributes to crizotinib-induced hepatotoxicity via the apoptotic pathway.

Pub. Date : 2019 Nov 15

PMID : 31639374






2 Functional Relationships(s)
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1 Crizotinib is an oral small-molecule tyrosine kinase inhibitor targeting anaplastic lymphoma kinase (ALK), ROS proto-oncogene 1, receptor tyrosine kinase (ROS1) and MET proto-oncogene, receptor tyrosine kinase (MET). Crizotinib ret proto-oncogene Homo sapiens
2 Crizotinib is an oral small-molecule tyrosine kinase inhibitor targeting anaplastic lymphoma kinase (ALK), ROS proto-oncogene 1, receptor tyrosine kinase (ROS1) and MET proto-oncogene, receptor tyrosine kinase (MET). Crizotinib ret proto-oncogene Homo sapiens