Title : ADP-Ribosylation Levels and Patterns Correlate with Gene Expression and Clinical Outcomes in Ovarian Cancers.

Pub. Date : 2020 Jan

PMID : 31594824






1 Functional Relationships(s)
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1 In addition, the levels and patterns of ADPRylation, PARP-1 protein, and gene expression correlated with clinical outcomes in response to platinum-based chemotherapy, with cancers exhibiting the highest levels of ADPRylation having the best outcomes independent of BRCA1/2 status. Platinum poly(ADP-ribose) polymerase 1 Homo sapiens